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Mice fed with HFD display higher body weight increase compared to control mice (mice fed with Chow Diet, CD) (Supplementary Figure 1A)

As a weight loss approach, Glp-1 agonists further slow down the metabolism to control blood sugar

Patients should increase fiber gradually to minimize gastrointestinal discomfort, which can be more pronounced with tirzepatide's delayed gastric emptying

Consider a lower dosage You cant always control how fast you lose weight on tirzepatide, but studies show that higher doses usually lead to faster weight loss

Starting at a lower dose and taking berberine with food significantly reduces the likelihood of digestive issues for most people

Simple steps like eating smaller meals, staying hydrated, and avoiding heavy foods can help manage symptoms