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Grapefruit does not have a direct chemical interaction with Ozempic, so it wont make side effects worse through a drug interaction
Incidence of progression of retinal disease in individuals with mild NPDR at baseline (R1M0, R1M1) New onset of the composite of moderate-to-severe NPDR (R2M0, R2M1) or PDR (R3M0, R3M1) was reported in 49 of 1053 (4.7%) tirzepatide-exposed individuals and 37 of 1089 (3.4%) tirzepatide-unexposed individuals with mild NPDR at baseline (R1M0, R1M1)