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A review of acetaminophen poisoning

Experimental Section 2.1

Collectively, this study identifies GGCT as a metabolic switch that diverts Gln flux toward GSH synthesis to maintain redox homeostasis, while enhancing glucose-fueled anaplerosis into the TCA cycle to sustain cell proliferation

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Gpx4, an antioxidant enzyme, protects T cells from excessive ROS-induced oxidative stress and prevents iron-mediated cell death

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