Dimers enhance activity by linking two molecules of artemisinin, such as a 2-5-fold increase in anti-malarial activity and stronger inhibition of the PI3K/Akt pathway, which can overcome tumor resistance (Yue et al., 2023
Dihexa: Bypasses upstream steps
Available from: Almoshari Y
Antidepressant Medications Selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs), and tricyclic antidepressants (TCAs) are used to treat a wide variety of mental health conditions like depression, anxiety, mood swings, obsessive-compulsive disorder (OCD), panic disorder, phobias, and post-traumatic stress disorder (PTSD)
Study design In this prospective cross-over study, five female and five male NZW rabbits each received four treatments with buprenorphine (Vetergesic vet, 0.3 mg/mL, Orion Pharma, Danderyd, Sweden), with 2-week wash-out periods between treatments
doi: 10.1056/NEJMoa073493 16 International Multiple Sclerosis GeneticsCWellcome Trust Case ControlCSawcerSHellenthalGPirinenMSpencerCCet al