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A third target is intestinal microbiomes and metabolic endotoxemia

Common side effects with dose escalation include nausea, vomiting, constipation, and reduced appetite, typically occurring most intensely for 1-2 weeks after each dose increase before tolerating improves

All in all, despite recent progress in the field, the detailed mechanisms of ferroptosis are still largely unknown and a significant amount of research remains to be developed in this new exciting area of research

Miteva T, Jordanova R, Iskrov G, et al

Open 7 , e2425614 (2024)

Reynolds JC, Lai RW, Woodhead JST, Joly JH, Mitchell CJ, Cameron-Smith D, Lu R, Cohen P, Graham NA, Benayoun BA, Merry TL, Lee C