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NNMT inhibition combined with exercise enhances skeletal muscle endurance and grip strength in aged mice

Generally, the effects of water-soluble vitamin injections can last from a few days to a couple of weeks

No trials specifically enrolled elderly individuals, those with significant cardiovascular disease, individuals with active cancer, or pregnant/breastfeeding women

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Early work, including in the Journal of Medicinal Chemistry, has mapped these relationships to guide the design of next-generation NNMT inhibitors

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