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Regulated cell death (RCD) in cancer: key pathways and targeted therapies

Adenoviral-mediated methods to overexpress sarcoplasmic-endoplasmic reticulum Ca2+/ATPase (SERCA) have shown promise in preclinical and early-phase clinical trials

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Cytoplasmic and Mitochondrial Tetrahydrofolate Interconversions A member of the folate metabolism family of enzymes, encoded by the MTHFD1 gene, can generate NADPH in the course of the conversion of N 5 , N 10 -methylene-tetrahydrofolate (5,10-methylene-THF) to 5,10-methenyl-THF