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[16] According to NICE guidelines (CG61), IBS is diagnosed based on clinical criteria when patients experience abdominal pain or discomfort that has been present for at least 6 months, is associated with defecation or a change in bowel habit, and with at least two of the following: altered stool frequency, altered stool form, altered stool passage, mucus in stool, or bloating/distension
10.2215/cjn.0000000000000326 20 ChenJ.LiuQ.ZengL.HuangX
While this is central to their effectiveness, it can also disrupt normal bowel habits
Provides clean and effective formulation
Lancet 363 , 21392141 (2004)
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