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Secretory functions of macrophages in the human pancreatic islet are regulated by endogenous purinergic signaling

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To further delineate the mechanism of PAM deficiency on GLP-1 resistance, pancreas-specific (Pdx-Cre Pam fl/fl ) and induced whole body knockout mice (PamKO) were studied

Long-term studies indicate sustained results when fat cells are dissolved and eliminated from the body through natural fat metabolism processes

2022;4(3):fcac089