Upon ligand binding, Notch undergoes sequential proteolytic cleavage, releasing the Notch intracellular domain (NICD), which translocates to the nucleus and influences transcription through the RBPJ/CSL complex
Baar et al, Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging
Additionally, IV hydration therapy may be employed to combat dehydration often seen in patients with chronic inflammatory conditions, ensuring that patients maintain optimal hydration levels for overall health and well-being
Araujo et al., 2007)
Diabetes 61 , 542546, (2012)
Flavonoids have been considered as a secondary ROS scavenging system in plants experiencing damage to the photosynthetic apparatus, due to the excess excitation energy (Fini et al., 2011)