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Additionally, geographic bias may limit generalizability: a potential geographic bias exists, as a substantial proportion of the included trials were conducted in North America and Europe, limiting generalizability to underrepresented populations in Asia, Africa, and South America

However, occasional use at recommended doses has rarely been linked to problems in breastfed infants

doi: 10.1038/s41598-019-55524-w 5 ChangJ

Sublingual liquid formulations represent an alternative delivery method

Do not introduce new stressors or make major life changes if avoidable

The physician-supervised program feels safe and effective