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About this article Cite this article Zhao, J.V., Burgess, S., Fan, B

Administer once weekly, on the same day each week, at any time of day

Patients carrying certain GLP1R variants may experience different levels of GLP-1 signaling efficiency, which can affect overall treatment tolerability and efficacyfactors that complement (but do not replace) proper injection technique and site rotation

Some patients report vomiting or regurgitation, though these symptoms typically resolve within 46 weeks as the body adapts

Distinctions between the bioavailability of various drugs based on their route of administration, pharmacological and physiological properties may explain why neuroprotective compounds in TBI studies have not been successful so far at the clinical level