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Phosphinic peptides often share structural similarities with the transition-state of peptide substrate upon hydrolysis ( Figure 11 The phosphinic group is, as compared to, e.g., thiols and hydroxamic acids more weakly binding to zinc ions in metalloproteases and a significantly improved selectivity could be achieved by systematic variations of the side chains at P1 and P2 positions of 43

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When you're working with high-purity research peptides, the details aren't just details

It affects transforming growth factor beta (TGF-) signaling, which plays a central role in scar formation