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This endogenous activation provides sustained cellular protection compared to direct free radical scavenging by exogenous antioxidants

However, initial studies of tesofensine for these neurological conditions wasn't successful

Innovations such as continuous-flow synthesis, OoC models, and machine-learning-driven strategies are required to improve reproducibility, scalability, and predictive safety assessments

B9 (Folate) & B12 (Cobalamin): Critical for brain function, mental clarity, and preventing fatigue-related mood dips

In addition to alterations in the mechanistic functions of brain endothelial cells, BBB breakdown is evident by degeneration of both endothelial cells and pericytes [101]