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These categories matter in compliance: These go through Phases I-III clinical trials, get reviewed, and are approved for specific indications and doses

Although the statute requires that the PE and MP GPCIs reflect full relative cost differences, section 1848(e)(1)(A)(iii) of the Act requires that the work GPCIs reflect only one-quarter of the relative cost differences compared to the national average

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Do not freeze unless specified by product labeling or lab SOPs