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The engineered CAR used the scFv regions previously described 42,54 but with the CD8a hinge/TM domains and 4-1BB costimulatory domain

Although these findings suggest potential benefits of GABA-related interventionsgiven carnosines proposed modulation of GABAergic activity and zinc/copper homeostasisthe mechanism remains unclear, and replication in larger, independent samples is needed (183)

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The G2-phase DNA-damage checkpoint