J Pharmacol Exp Ther 294:735745 Nepovm A, Podlipn R, Soudek P, Schrder P, Vanek T (2004) Effects of heavy metals and nitroaromatic compounds on horseradish glutathione S-transferase and peroxidase
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The studies show increased IL-4, IL-5, and eosinophils.[ref][ref] Related article: Microplastics Research Roundup PFAS or PFOAs : Inhalation of PFOS or PFAS has been shown in animal studies and epidemiological studies to cause inflammation and trigger IL-1B in the lungs
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The picture that emerges from these experiments is that endogenous GSH is not just an inhibitor of inflammation, but it is required to allow a proper response to infection, and direct the migration of inflammatory PMN away from the lung, where they cause ARDS, and towards the site of infection, where they kill bacteria (Figure 6)
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