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After the acclimatization period, mice were assigned to sham exposure (SHAM), and SE groups

It effectively counteracts the damage induced by stress, cysteamine, and ethanol in experimental models, outperforming several standard treatments

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Am J Gastroenterol

For instance, IL-22 signaling through IL-22R is essential for thermogenesis in white adipose tissue, as demonstrated in adipocyte-specific IL-22R KO mice