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Some patients breeze through this phase with minimal discomfort, while others find it more challenging

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The assessment of skin irritation showed no erythema or edema in 48 h, which was confirmation of local tolerability

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Target dose: 1 to 3 grams daily, split into two or three doses before meals

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Dose Escalation Timing and Tolerability Adjustments Standard protocol advances dosing every 4 weeks, allowing the body to adapt

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