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Researchers considering extended protocols should be aware that this safety gap exists and should monitor for unexpected effects in tissues where NNMT has normal physiological functions

doi:10.1016/j.bmcl.2018.07.009

People with dietary restrictions, such as vegans and vegetarians, who may not get sufficient B12 from their diet, or those with absorption issues, like those with pernicious anemia or gastrointestinal disorders, also often qualify

This general rule applies to maintaining consistent supplementation schedules for vitamins)

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