Abbreviations CGRP: Calcitonin gene-related peptide CSD: Cortical spreading depolarization REFORM: Registry for Migraine ICHD-3: International Classification of Headache Disorders, 3rd edition IQR: Interquartile range FHM: Familial hemiplegic migraine TCC: Trigeminocervical complex BOLD: Blood oxygenation level-dependent References Stovner LJ, Nichols E, Steiner TJ (2018) Global, regional, and national burden of migraine and tension-type headache, 19902016: a systematic analysis for the global burden of Disease Study 2016
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Their analysis found that people taking glucagon-like peptide-1 (GLP-1) receptor agonists had a significantly lower risk of serious cardiovascular problems compared with those who received a placebo
Younger animals typically exhibit higher levels of synaptic plasticity [21], more efficient neuronal signaling pathways [37], while aging, which is associated with declines in neurogenesis and reduced neural adaptive capacity, [22] which are related to impairments in cognitive function
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Both peptides lack tumor-promoting activity in published studies, and neither affects cortisol, prolactin, or other hormonal axes
