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This enzyme requires the FAD coenzyme form of riboflavin for this reduction reaction, thus, emphasizing the role of riboflavin in the formation of reduced, active, glutathione ( Second, it has been shown that the oxidation of dihydroriboflavin, the reduced riboflavin, forming oxidized riboflavin can deactivate lipid peroxides, emphasizing the independent antioxidant property of riboflavin ( Third, riboflavin effects on antioxidant enzymes activities, including superoxide dismutase (SOD) ( Important to note, UV-B irradiation, the atmospherically predominant UV radiation, has been shown to reduce the neuroprotective effects of riboflavin both in vitro and in vivo

Weishaupt JH, Bartels C, Polking E, Dietrich J, Rohde G, Poeggeler B, et al

Kronenberg F

Each vial contains 50 mg of lyophilized powder with a verified purity of 98% (HPLC)

These proteins facilitate the transfer of PC from the endoplasmic reticulum to other cellular membranes, such as those of the mitochondria and the plasma membrane

1975 Feb 25;250(4):14221426