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Discussion In this study, leveraging non-viral LNPs and the HITI-mediated genome editing method, we engineered a secretion-enabled Exe4 peptide, scExe4, and developed an in vivo scExe4 peptide production reservoir via knock-in into mouse liver cells

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A meta-analysis found a trend toward decreased ototoxicity (ear toxicity or hearing impairment) in patients receiving amifostine infusion prior to cisplatin chemotherapy (Duval 2012)

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