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Serum analysis of 32 patients with high-frequency migraine revealed abnormally low levels of alpha-lipoic acid (ALA) and lactate, along with abnormally high levels of peroxides in 46.9% of the patients, further supporting the role of oxidative stress and metabolic alterations in the pathophysiology of migraine (40)

Sitohang IBS, Ninditya S

Preclinical studies in animal models have reported associations with metabolic and adipose-tissue endpoints

Moreover, the rising prevalence of obesity and type 2 diabetes (T2D) globally continues to significantly boost market demand, as GLP-1 agonists play an essential role in the treatment and management of these conditions

Protein post-translational modifications regulated by butyrate Acetylation Lysine acetylation (Kac), a critical post-translational modification, involves the covalent attachment of acetyl groups to lysine residues, dynamically controlling protein functions, cellular signaling, and epigenetic states

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