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NIH reviews highlight potential investigational interest in conditions such as sarcopenia or cachexia

Taking CLA alone on an empty stomach might cause mild discomfort or nausea for some people

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Conversely, weight loss and metabolic improvement can reduce friction, sweating, and inflammatory burden in intertriginous areas

However, while youll notice these appetite-suppressing effects quickly, the actual weight loss resulting from your reduced caloric intake will take several weeks to become apparent

Anecdotally, many researchers working on specific, localized injuries prefer localized administration, believing it provides a more targeted and potent effect