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To overcome venetoclax resistance, appropriate inhibitors are being developed in parallel (10,81)

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101 Hyperactivation of the PI3K pathway, a lipid kinase that promotes proliferation and nutrient uptake in response to growth signals, has been implicated in breast and endometrial cancers, providing a possible mechanism for hormonal therapy evasion

During this period, patients may find it best to opt out of late-night activities and intense workouts