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Your healthcare provider may recommend baseline assessment of reflux symptoms and consider concurrent acid-suppressive therapy with proton pump inhibitors if needed

Indeed, a subsequent clinical trial showed that pioglitazone may be therapeutic in patients with TC bearing PPFP (Giordano et al., 2018)

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MiyazatoMTohyamaKTouyamaMNakamuraHOshiroTUedaSet alEffect of continuous positive airway pressure on nocturnal urine production in patients with obstructive sleep apnea syndrome