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In perimenopausal or postmenopausal women, early data support efficacy regardless of reproductive stage , although research focused specifically on perimenopause remains limited

The clinical trial with ROSE-010 demonstrated its efficacy in acute pain relief for IBS patients and correlation between serum GLP-1 levels and abdominal pain severity further supports the role of GLP-1R agonists in managing visceral pain

9 Richie JP Jr, et al

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