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For semaglutide, treatment should be discontinued at least 2 months before conception attempts

The authors write that Louwagies case report (and others) should not detract from the substantial value of GLP-1 based therapies, but they do speak yet again to the importance of individualized therapy

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Protein kinase CK2: structure, regulation and role in cellular decisions of life and death

10.1016/j.biopha.2023.115263 91 MasoudiF

For the vast majority of people, the benefits of improved metabolic health and weight reduction far outweigh the short-lived discomfort of the adjustment period