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Semaglutide 2.4 mg (Wegovy), a once-weekly GLP-1 receptor agonist licensed by the MHRA and recommended by NICE (Technology Appraisal TA875) for use in specific circumstances, demonstrated mean weight loss of approximately 14.9% from baseline at 68 weeks in the STEP 1 phase 3 trial (Wilding JPH et al., N Engl J Med

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