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Supply issues Making the GLP-1 drug is a multi-step process, which is slow and capital-intensive

The overall heterogeneity levels were 24.4% (95% uncertainty intervals, 0 and 54.9%) for nonfatal MI (moderate), 11.1% (95% uncertainty intervals, 0 and 48.0%) for nonfatal stroke (low) and 15.8% (95% uncertainty intervals, 0 and 49.9%) for CV death (moderate) (Additional file 1: Table S3)

But life is difficult, he said

Large CVOTs and other smaller studies have shown an association between the use of GLP-1RAs and DPP-4i on the relative rates of HF hospitalization

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The change allows Hims & Hers to sell cheaper versions of GLP-1s like Wegovy