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Journal of Biological Chemistry 288, 2649726504

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Briefly, recombinant GSTO1 was diluted into 50 mM Tris-HCl (pH 8.0) buffer containing the fluorophore 1,8 ANS (0.3 mM) to a final concentration of 0.3 mg ml 1

The primary comparators of interest were all licensed doses of injectable GLP-1 RAs approved for the treatment of T2Donce-weekly dulaglutide, twice-daily exenatide, once-weekly exenatide extended-release, once-daily liraglutide, once-daily lixisenatide, and once-weekly injectable semaglutide

(1986) established that selenocysteine (Sec), a seleno-amino acid, constituted the catalytic active site of GPx and was incorporated into the peptide sequence by the termination codon, UGA [5,6,7]

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