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The conformationally constrained peptide containing proline ( 7C ) and peptides with more complex amino acids such as arginine, methionine, and cysteine ( 8C, 9C , and 10C ) were all compatible, affording yields between 48 and 72%

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Tirzepatide, the dual GLP-1/GIP agonist marketed as Zepbound for obesity and Mounjaro for type 2 diabetes, is currently the most potent approved agent in the class

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