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They begin to suffer from anemia, nerve damage, and other problems

16 Matthias Tschp and his team discovered that dual agonists targeting both GLP-1 and GIP receptors (GIPR) are more effective in treating diabetes than those targeting only GLP-1R

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Sci Rep 15 , 37150 (2025)

Furthermore, fAD organoids exhibited signs of neuronal apoptosis, with increased levels of cleaved Caspase-3 (c-CASP3) and TUNEL signals, and mitochondrial dysfunction markers (NDUFA4, NDUFA6, NDUFB11) in Day 60 fAD organoids [2]

Glutathione peroxidase (GPx, EC No