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Protein purification XPO1 (also known as CRM1) was purified as described 109 with a minor modification: 4 L of LB medium were used instead of 6 L

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Light emission at 615 nm ( ex =480 nm) was quantified at room temperature in 1 ml quartz cuvette

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The good tolerability and safety profile for the use of the lecithin-based formulation of quercetin was confirmed based on the extensive documentation previously reported and supported by a large number of subjects supplemented with a dosage range from 250 mg to 1500 mg per day, up to a maximum of 3 months, without mild, moderate, or serious side effects