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& Smith, C

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J Clin Endocrinol Metab 46:784, 1981

The high expression of CROT in male (statistically significant) and female (trend to increase) livers suggest that it is possible that ibuprofen treatment induces peroxisomal oxidation of medium and long chain fatty acids metabolism as a compensatory mechanism due to an overload of -oxidation of fatty acids in mitochondria