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Patients with significant gastrointestinal side effects, those in dose-escalation phases, or those with gastroparesis may be advised to withhold Rybelsus temporarily

3 , 4 Researchers from Alliance Medical Ltd

These differences underscore the difficulty in defining HFimpEF, complicating efforts to standardize diagnosis, assess prognosis, and guide therapy across different healthcare settings

Furthermore, GLP-1-RAs may influence this mechanism indirectly by enhancing insulin sensitivity and exerting anti-inflammatory effects [84, 96]