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Finally, none of the multi-agonists at lower doses, nor metformin, had a beneficial effect on ovarian cyclicity or any other gonadal parameter, such as ovarian and uterus weights and circulating LH levels (Suppl

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Wegovy mimics one hormone (GLP-1), while retatrutide mimics three (GLP-1, GIP and glucagon)

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The glucagon receptor agonism, whilst counterintuitive given glucagon's role in raising blood glucose, is thought to increase energy expenditure and promote hepatic fat oxidation whilst reducing lipogenesis effects that may offer potential benefits in metabolic dysfunction-associated steatotic liver disease (MASLD)

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Respond to dietary adjustment and OTC remedies within 3 to 7 days

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