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4.5 Additional factors that disrupt the balance when their activity is removed in sensitized backgrounds 4.5.1 Splicing factors Many splicing factors have been identified as potentially being involved in the proliferation vs differentiation decision based on a reduction or loss of their activity enhancing tumor formation

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Both compounds share the same regulatory timeline: moved to Category 2 in 2023, removed from Category 2 in April 2026, and scheduled for PCAC review on July 23, 2026

This can be done in the upper arm, abdomen, or thigh and offers flexibility in timing, as it can be taken regardless of meals