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a , Hydroxylation of C 2 would preclude the incorporation of an O 18 label as no equilibrium between a ketone and a gem-diol form exists for this hydroxylation product
The DDC encoded enzyme is dependent upon pyridoxal phosphate (PLP: vitamin B6-derived cofactor) for activity
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Polymorphisms are also present in GSTs of the alpha class and omega class, with the isoenzymes GSTA1-1, GSTA2-2 and GSTO1-1 and GSTO2, respectively 32
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