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11.5 Pharmacokinetics and bioavailability It is evident that following oral administration, resveratrol is rapidly absorbed in the gastrointestinal tract (75%) with an extensive first-pass metabolism in the intestine and liver, lowering its oral bioavailability (ranging from 2.6 to 75% in humans and 2029% in rats fed 50 mg/kg) [198]

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If the patient has taken a drug which could delay the gastric emptying, then activated charcoal can be given even at a later stage

If morning dosing is logistically impossible

#1725124, Bio-Rad) and 50 ng of cDNA per well