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Many peptides lack stability and must be administered subcutaneously

The SELECT trial (Lincoff et al., NEJM 2023, NCT03574597) extended Semaglutide research to cardiovascular outcomes in 17,604 adults with obesity and prior cardiovascular disease (no T2D) over a mean ~34-month follow-up

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As long as the rapid weight loss continues, the shedding can carry on