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PMCID: PMC9344768

Targeting the MGBA offers a novel, translational approach to intervention that may ultimately contribute to healthier brain aging and improved outcomes across the lifespan

14 Increasing nevus counts are found in individuals who tend to sunburn rather than tan following sun exposure and correlate with the degree of freckling

For researchers designing studies focused specifically on hypothalamic melanocortin signaling, PT-141 offers the advantage of reduced confounding pigmentation variables, whereas Melanotan II remains the preferred tool when studying the full spectrum of melanocortin receptor biology or when MC1R-mediated effects are part of the research question

Biochemical Society transactions 10 , 7879 (1982)