Arron, orcid.org/0000-0002-6427-1278
While there are big reasons for this, like well-publicized research about the impact alcohol has on health and a general decline in social activities among Gen Z, one connection thats only just getting some attention is that between GLP-1 medications, like semaglutide and tirzepatide, and alcohol use
A complete medical history assessing for gut inflammation, celiac disease, GERD, recent nitric oxide use in surgery, and genetic factors like MTHFR should trigger a closer look at B12 adequacy even with a normal homocysteine (HCY) plasma test
10.1089/jop.2018.0151 144 PostorinoE
No human dose-response data exists
It preferentially transports branched AAs, and their substrates including Phe, Trp, Leu, Ile, Met, His, Tyr, Val and Thr, most of which are essential AA