Approved Indications: Type 2 Diabetes Mellitus (T2DM): As an adjunct to diet and exercise to improve glycemic control Cardiovascular Risk Reduction: Reduction in major adverse cardiovascular events (MACE)including CV death, non-fatal myocardial infarction, and non-fatal strokein adults with T2DM at elevated cardiovascular risk Mechanism of Action: A GLP-1 receptor agonist, semaglutide enhances glucose-dependent insulin secretion, suppresses glucagon release, and delays gastric emptyingresulting in improved glycemic control and favorable metabolic effects
[DOI] [PMC free article] [PubMed] [Google Scholar] 55.Hsieh MJ, Liu HT, Wang CN, Huang HY, Lin Y, Ko YS, Wang JS, Chang VH, Pang JS
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