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Often, Glutathione is broken down in the body very quickly, resulting in not being able to reach the cells where it is needed

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Genome Res 19:15071515 Tujios S, Fontana RJ (2011) Mechanisms of drug-induced liver injury: from bedside to bench

Also pretreatment with glutathione significantly decreased sensitivity of mPTP to calcium (Figure 2B) which could indicate increased or restored Ca 2+ capacity of mitochondria of old rat heart