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Unlike the illicit use of anabolic steroids, IGF-1 in medicine is administered under strict supervision and is intended to address specific health concerns, such as growth hormone deficiency or sarcopenia, the age-related loss of muscle mass

A dose that supports one organ system may be excessive for another

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Finally, obese mice lost weight more effectively when dexamethasone and GLP- 1 were conjugated than when GLP- 1 was used alone [142]