In January 2025, the FDA quietly took down its draft Diversity Action Plan guidance from its website, and by May, Novo Nordisk had elected to remove its own gender-quota policy for US operations
Yamada et al., 1996) and its precursor choline (Aquilonius et al., 1976
This development raises a fundamental question: does the future of oral GLP-1 therapy belong to small molecules rather than peptides
The trick was in adding long fatty acid chains that grabbed onto albumin the most abundant protein found in the blood allowing the GLP-1 lookalike to hide from enzymes that would chop it up
Enhanced Satiety and Appetite Regulation: Similar to semaglutide, tirzepatide slows gastric emptying and influences appetite centers, but its dual mechanism can lead to more pronounced effects on satiety and food intake reduction
However, with inverse variance weighted Mendelian randomization, no causal relationship between serum vitamin C levels and MASLD risk was observed (OR = 0.82, p = 0.502)