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In a separate experiment, 60 male Balb/c mice (6 weeks old) were intraperitoneally infected with 200 L of bacterial suspension (1 10 9 CFU/mL) and randomly divided into four groups

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Sleep deprivation increases IL-4 and IL-13 (Th2 cytokines that drive allergic inflammation) while decreasing IL-10 and IFN-gamma (anti-allergic cytokines)