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When it comes to compounds like Retatrutide and Tirzepatide, their extended pharmacological properties dictate longer dosing intervals compared to many traditional research chemicals

doi: 10.1016/j.peptides.2019.170224 37 McIntoshCHWidenmaierSKimS

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IGF-1 LR3 introduces two modifications: R3 substitution : replacement of glutamic acid at position 3 (Glu3) by arginine (Arg3)

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